Please use this identifier to cite or link to this item: https://repositorio.ufma.br/jspui/handle/123456789/779
Title: Laparoscopic guided local injection in the X-linked muscular dystrophy mouse (mdx) diaphragm: an advance in experimental therapies for Duchenne Muscular Dystrophy1
Authors: LESSA, Thais Borges
CARVALHO, Rafael Cardoso
SPAGNOLO, Júlio David
SILVA, Luis Claudio Lopes Correia da
CORTOPASSI, Silvia Renata Gaido
AMBRÓSIO, Carlos Eduardo
Keywords: Diaphragm
Injections
Muscular Dystrophy
Duchenne
Laparoscopy
Mice
Issue Date: 2014
Publisher: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Citation: LESSA, T. B. et al. Laparoscopic guided local injection in the X-linked muscular dystrophy mouse (mdx) diaphragm: an advance in experimental therapies for Duchenne Muscular Dystrophy1. Acta Cirúrgica Brasileira, São Paulo, v. 29, n. 11, p. 715-720, 2014. DOI: http://dx.doi.org/10.1590/S0102-86502014001800004
Abstract: PURPOSE: To investigate the development of a laparoscopy technique for local injection into the X-linked muscular dystrophy (mdx) diaphragm. METHODS: It was used 10 mice Balb/C57 and 5 mdx mice and three differents decubitus type were tested: the right lateral, supine, and supine decubitus with 20 degrees elevation of the forelimb. Abdominal caudal face and the 10 intercostal space were tested as spot to introduce the needle into the diaphragm. RESULTS: Supine position with elevation of 20 degrees forelimb and the 10th intercostal space are the beneficial position to apply a local injection. CONCLUSION: It was proved to be possible to perform the laparoscopy technique in the X-linked muscular dystrophy diaphragm and this requires a specific position and technique during the surgery.
Description: Creative Commons License This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC-BY-NC)
URI: http://hdl.handle.net/123456789/779
ISSN: 1678-2674
Appears in Collections:Artigos - Zootecnia

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